CV

https://www.dzne.de/forschung/forschungsbereiche/grundlagenforschung/forschungsgruppen/vorberg/curriculum-vitae/

Publikationen

• Hofmann, J.P., Denner, P., Nussbaum-Krammer, C., Kuhn, P.H., Suhre, M.H., Scheibel, T., Lichtenthaler, S.F., Schätzl, H.M., Bano, D. and Vorberg, I.M. (2013). Cell-to-cell propagation of infectious cytosolic protein aggregates. Proc Natl Acad Sci, 110, 5951-5956.
• Wolf H., Hossinger A., Fehlinger A., Büttner S., Sim V., McKenzie D. amd Vorberg I. (2015). Deposition pattern and subcellular distribution of disease-associated prion protein in cerebellar organotypic slice cultures infected with scrapie. Front Neurosci 9, 410. doi: 10.3389/fnins.2015.00410.
• Liu, S., Hossinger, A., Hofmann, J.P., Denner, P., Vorberg, I.M. (2016). Horizontal transmission of cytosolic Sup35 prions by extracellular vesicles. MBio 7(4), pii: e00915-16. doi: 10.1128/mBio.00915-16.
• Fehlinger, A., Wolf, H., Hossinger, A., Duernberger, Y., Pleschka, C., Riemschoss, K., Liu, S., Bester, R., Paulsen, L., Priola, S.A., Groschup, M.H., Schätzl, H.M., Vorberg, I.M. (2017). Prion strains depend on different endocytoc routes for productive infection. Sci Rep 7: 6923.
• Sachdev R., Kappes-Horn K., Paulsen L., Duernberger Y., Pleschka C., Denner P., Kundu B., Reimann J., Vorberg I. (2018). Endoplasmic Reticulum Stress Induces Myostatin High Molecular Weight Aggregates and Impairs Mature Myostatin Secretion. Mol Neurobiol. doi: 10.1007/s12035-018-0997-9.
• Duernberger, Y., Liu S., Riemschoss K., Paulsen L., Bester R., Kuhn P.H., Schölling M., Lichtenthaler, S.F., Vorberg, I. (2018). Prion Replication in the Mammalian Cytosol: Functional Regions within a Prion Domain Driving Induction, Propagation, and Inheritance. Mol Cell Biol. 38(15). pii: e00111-18. doi: 10.1128/MCB.00111-18.
• Riemschoss, K., Arndt, V., Bolognesi, B., von Eisenhart-Rothe, P., Liu, S., Buravlova, O., Duernberger, Y., Paulsen, L., Hornberger, A., Hossinger, A., Lorenzo-Gotor, N., Hogl, S., Müller, S.A., Tartaglia, G., Lichtenthaler, S.F., Vorberg, I.M. (2019). Fibril-induced glutamine-/asparagine-rich prions recruit stress granule proteins in mammalian cells. Life Sci Alliance 2;2(4):e201800280. doi: 10.26508/lsa.201800280.
• Michiels, E., Liu, S., Gallardo, R., Louros, N., Mathelié-Guinlet, M., Dufrêne, Y., Schymkowitz, J.*, Vorberg, I.*, Rousseau, F.* (2020). Entropic bristles tune the seeding efficiency of prion-nucleating fragments. Cell Rep. 25;30(8):2834-2845.e3. doi: 10.1016/j.celrep.2020.01.098.
• Chakraborty P, Rivière G, Liu S, de Opakua AI, Dervişoğlu R, Hebestreit A, Andreas LB, Vorberg IM, Zweckstetter M. (2021). Co-factor-free aggregation of tau into seeding-competent RNA-sequestering amyloid fibrils. Nat Commun 12(1):4231. doi: 10.1038/s41467-021-24362-8.
• Liu, S., Hossinger, A., Heumüller, S.-E., Hornberger, A., Buravlova, O., Konstantoulea, K., Müller, S.A., Paulsen, L., Rousseau, F., Schymkowitz, J., Lichtenthaler, S.F., Neumann, M., Denner, P., Vorberg, I.M. (2021). Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions. Nat Commun. 12(1):5739. doi: 10.1038/s41467-021-25855-2.